For research use only, not for human or veterinary use. Samples of dissolution medium 5ml were withdrawn at different time intervals, suitably diluted and assayed for etoricoxib by measuring. Patients were given placebo the first day and then were challenged with oncedaily etoricoxib in 3 different doses. However, we make no warranty of merchantibility or any other warranty, express or implied. Understanding and correcting msds file upload errors during the file upload process in msds, users will often receive a popup message indicating the file was uploaded successfully, yet sometimes the data never reaches the staging area. Understanding and correcting msds file upload errors. Carbon monoxide, carbon dioxide, oxides of nitrogen, oxides of sulfur, hydrochloride, and other chlorinecontaining compounds. If you have moderate liver disease, you should not take more than 30 mg a day. The report is only responsible for the submitted samples except as otherwise noted. Stock solution of etoricoxib btransferred an accurately quantity 60.
Sds of etoricoxib, safety data sheets, cas 202409334. Material safety data sheets msds for itw ramset tools. Material safety data sheet msds replication defective recombinant aav vectors are noninfectious and nonhazardous materials as defined by osha 1919. Material safety data sheet prepared according to 29 cfr 1910. Suppliers name street address 595 southgate drive street address city guelph province ontario city province postal code n1g 3w6. None of the components is considered a reproductive hazard. The vectors may be used under biosafety level bsl1 conditions however they are generated under bsl2 conditions due to the use of hek293 cells in the production process. Sigmaaldrich 3050 spruce street saint louis mo 63103 usa. Transport information large batteries are considered to be dry cell batteries and are unregulated for purpose of transportation by the u. However, no warranty or representation, expressed or implied, is made as to the accuracy or completeness of the foregoing data and safety information. The information herein is based on data considered to be accurate as of the date of preparation of this material safety data sheet. Merging pdf files has become a common need for many people nowadays. Etoricoxib may be given to a broad range of patients without need for dosage adjustment, except in cases of hepatic insufficiency.
Etoricoxib is a non steroidal antiinflammatory agent, acting as a selective and orally active cox2 inhibitor, with ic50s of 1. Transfer to a chemical waste container for disposal in accordance with local regulations. Caution should be exercised in patients with a history of cardiac failure, left ventricular dysfunction, or hypertension and in patients with preexisting oedema from any other reason. This product is not classified as toxic by established criteria. People combine 2 similar files together many times to save their pc from becoming a mess. If there is clinical evidence of deterioration in the condition of these patients, appropriate. But there are very few methods available for doing so and not many of them are free.
Pdf, xml, xfo and any other electronic files rendered by an infosafe system for infosafe msds displayed is the intellectual property of acohs pty ltd. Formulation of etoricoxib into immediate release tablets. Etoricoxib sold under the trade name gencox is a selective cox2 inhibitor from mcolson research laboratories currently it is approved in more than 80 countries worldwide but not in the us, where the food and drug administration fda has required additional safety and efficacy data for etoricoxib before it will issue approval. Etoricoxib is a synthetic, nonsteroidal antiinflammatory drug nsaid with antipyretic, analgesic, and potential antineoplastic properties. Sc218446 etoricoxib revision date 30oct2014 disclaimer the information provided in this material safety data sheet is correct to the best of our knowledge, information and belief at the. Methods and material for containment and cleaning up. This online pdf compressor allows to compress pdf files without degrading the resolution dpi, thus keeping your files printable and zoomable. Accidental release measures contain spill and collect, as appropriate. Study the material safety data sheets for the hazards of the chemical, learn the instructions on handling, storage and the emergency measures in case of accident take our free online course to learn how to to properly apply and use your msds complete a full risk assessment for your workplace so that you can map out all the hazards into a single comprehensive coshh assessment. It provides an alternative to other selective and traditional nsaids in treating patients with arthritis and other painful conditions.
Send us your paper safety data sheets and well professionally scan and convert them to pdf format before indexing them. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. More sds files for chemicals 20232397 2023485 202348547 20235783 20238839 20243598 20244615 20244864 2024546 202463681. Argentina australia austria belgium brazil canada chile china czech republic denmark finland france germany hong kong hungary india ireland israel italy japan korea malaysia mexico netherlands new zealand norway poland portugal. Pfizer inc believes that the information contained in this material safety data sheet is accurate, and while it is provided in good faith, it is without warranty of any kind, expressed or implied. If no evidence of intolerance was seen, each patient was rechallenged with 60 or 90 mg of etoricoxib once daily according to the rheumatic condition 7 days later. Both referral procedures pertained to the safety of the cox2 inhibitor products, including etoricoxib, with a particular focus on gastrointestinal gi. Dermal 2,000 mgkg based on an assessment of the ingredients. Arcoxia tablet pi 111109 v3 wpcmk0663t082011 page 1 product information. This material safety data sheet should be provided to the attending medical doctor.
Etoricoxib is a novel cox2 inhibitor with high selectivity for cox2 106 cox2cox1 ratio, as compared to 35 for rofecoxib or 1. Etoricoxib is highly selective for cox2 ic 50 ratio, 344. Inhibition of cox2 may induce apoptosis and inhibit tumor cell proliferation and. Material safety datasheet 9sections section 1 product information product identifier drytype transformer whmis classification optional product use electrical manufacturers name hammond power solutions inc. Full text of material safety data sheets msds with occupational, environmental, and regulatory data, as well as names, cas registry numbers, and regulatory list numbers for pure substances, mixtures, and pesticides, many of which are the most heavily used chemicals in industry. If data for a hazard are not included in this document there is no known information at this time. Avoid raising and breathing dust, and provide adequate ventilation. Etoricoxib was included in previous chmp referrals on the safety of cox2 selective inhibitors in which concluded in 2004 and 2005. Etoricoxib specifically binds to and inhibits the enzyme cyclooxygenase2 cox2, resulting in inhibition of the conversion of arachidonic acid into prostaglandins. Stability studies in combine dosage form of etoricoxib and. Data supplied is for use only in connection with occupational safety and health.
Etoricoxib is a cox2 inhibitor with a high degree of selectivity for its target. Retention of material safety data sheets how long are you required to retain a material safety data sheet msds for the hazardous materials in use at your research laboratory or stockroom. Box 697, osprey, florida, 342290697 941 3779935 fax 941 3779539 cas number 67630. Safecoat flat pastel base zero voc suspected cancer agents. Responsibility, guarantee and law restriction are defined in the general service clauses.
234 1359 1205 923 1546 1551 1064 1468 1485 245 1420 175 1270 957 866 37 896 1476 753 610 1289 117 274 1319 1382 828 1214 1518 770 861 645 256 820 1334 305 1554 1311 1395 76 581 1383 410 79 1274 6 274 443 26